Publications

October 2020

Manuscript

Future Oncology

October 2020

Manuscript

Journal of Medical Economics

Flatiron-authored

October 2020

Manuscript

Future Oncology

October 2020

Manuscript

Friends of Cancer Research

Flatiron-authored

Prospective validation of a clinical tool developed with machine learning to identify high-risk patients with cancer and reduce emergency department visits

Coombs, L, Orlando, A, Adamson, BJS, Griffith, SD, Lakhtakia, S, Rich, A, Shaw, P, Wang, X, Miksad, RA, Mooney, K

October 2020

Abstract

ASCO Quality Care Symposium

Flatiron-authored

October 2020

Manuscript

Leukemia and Lymphoma

October 2020

Manuscript

OncoImmunology

September 2020

Manuscript

Cancer Medicine

Real-world outcomes among HER2+ metastatic breast cancer patients with brain metastases

Lindegger, N, Ike, C, Schwartz, NRM, Surinach, A, Liu, Y, Forero-Torres, A, DeBusk, K

September 2020

Abstract

ESMO Annual Congress

September 2020

Abstract

ESMO Annual Congress

September 2020

Manuscript

Applying Big Data to Address the Social Determinants of Health in Oncology Workshop

Flatiron-authored

STK11 (LKB1) mutations in metastatic NSCLC: prognostic value in the real world

Shire NJ, Klein, AB, Golozar, A, Collins, JM, Fraeman, KH, Nordstrom, BL, McEwen, R, Hembrough, T, Rizvi, NA

September 2020

Manuscript

PLoS One

A roadmap for developing study endpoints in real-world settings

Baxi, SS, Koontz, L, Mahoney, N, Torres, AZ, Bourla, AB

August 2020

Manuscript

Duke-Margolis Center for Health Policy

Flatiron-authored

Daratumumab-lenalidomide-dexamethasone vs standard-of-care regimens: Efficacy in transplant-ineligible untreated myeloma

Durie, BGM, Kumar, S, Usmani, SZ, Nonyane, BAS, Ammann, EM, Lam, A, Kobos, R, Maiese, EM, Facon, T

August 2020

Manuscript

American Journal of Hematology (AJH)

Real-world survival of heavily pretreated patients with refractory HR+, HER2-metastatic breast cancer receiving single-agent chemotherapy-A comparison with MONARCH 1

Rugo, HS, Dieras, V, Cortes, J, Patt, D, Wildiers, H, O'Shaughnessy, J, Zamora, E, Yardley, DA, Carter, GC, Sheffield, KM, Li, L, Andre, VAM, Derbyshire, RE, Li, XI, Frenzel, M, Huang, Y, Dickler, MN, Tolaney, SM

August 2020

Manuscript

Breast Cancer Research and Treatment

Analytic considerations for constructing real-world comparator cohorts

Tan, K, Segal, BD, Bryan, J, Curtis, MD, Nussbaum, NC, Miksad, RA, Samant, MK, Sarkar, S, Torres, AZ

August 2020

Abstract

Joint Statistical Meeting

Flatiron-authored

Retrospective analysis of real-world data to determine clinical outcomes of patients with advanced non-small cell lung cancer following cell-free circulating tumor DNA genomic profiling

Madison, RW, Schrock, AB, Castellanos, EH, Gregg, JP, Snider, J, Ali, SM, Miller, VA, Singal, G, Alexander, BM, Venstrom, JM, Chung, JH

August 2020

Manuscript

Lung Cancer

Flatiron-authored

An enhanced prognostic score for overall survival of patients with cancer derived from a large real-world cohort

Becker, T, Weberpals, J, Jegg, AM, So, WV, Fischer, A, Weisser, M, Schmich, F, Rüttinger, D, Bauer-Mehren, A

July 2020

Manuscript

Annals of Oncology

July 2020

Manuscript

The Oncologist

Organ dysfunction in advanced melanoma patients treated with immune checkpoint inhibitors

Spillane, S, Baxi, SS, Torres, AZ, Lenis, D, Freedman, AN, Mariotto, A

July 2020

Manuscript

The Oncologist

Flatiron-authored

The adoption of immune checkpoint inhibitors and patterns of care at the end of life

Riaz, F, Gan, G, Li, F, Davidoff, AJ, Adelson, KB, Presley, CJ, Adamson, BJS, Shaw, P, Parikh, RB, Mamtani, R, Gross, CP

July 2020

Manuscript

JCO Oncology Practice

Flatiron-authored

July 2020

Manuscript

The Oncologist

Patient characteristics, treatment patterns, and outcomes in patients with triple-class-refractory multiple myeloma

Mehra, M, Vogel, M, Valluri, S, Nair, S, Schecter, J, Slowik, R, Jagannath, S, Weisel, K, Usmani, SZ

June 2020

Abstract

Congress of the European Hematology Association

June 2020

Manuscript

Advances in Therapy

June 2020

Manuscript

JAMA Open

Flatiron-authored

Evaluating the impact of oncology care model reporting requirements on biomarker testing and treatment

Castellanos, EH, Orlando, A, Ma, X, Parikh, RB, O'Connell, G, Meropol, NJ, Hamrick, HJ, Adamson, BJS

June 2020

Manuscript

Journal of Oncology Practice

Flatiron-authored

Prior treatment time impacts survival outcomes in metastatic breast cancer

Rocque, GB, Gilbert, A, Williams, CP, Kenzik, KM, Nakhmani, A, Kandhare, PG, Bhatia, S, Burkard, ME, Azuero, A

June 2020

Manuscript

JCO Clinical Cancer Informatics

Clinical and genomic characteristics of small-cell lung cancer in never-smokers

Thomas, A, Mian, I, Tlemsani, C, Pongor, L, Takahashi, N, Maignan, K, Snider, J, Li, G, Frampton, GM, Ali, SM, Kim, S, Nichols, S, Rajapakse, V, Guha, U, Sharon, E, Fujimoto, J, Moran, CA, Witstuba, II, Wei, JS, Szabo, E, Torres, AZ, Carson, KR

May 2020

Manuscript

Chest

Flatiron-authored

Chromosome 1 abnormalities and survival of patients with multiple myeloma in the era of novel agents

Giri, S, Huntington, SF, Wang, R, Zeidan, AM, Podoltsev, NA, Gore, SD, Ma, X, Gross, CP, Davidoff, AJ, Neparidze, N

May 2020

Manuscript

Blood Advances

May 2020

Manuscript

Journal of Oncology Pharmacy Practice

May 2020

Manuscript

Clinical Lymphoma; Myeloma; and Leukemia

Generalizable machine learning framework for predictive modeling of patient outcomes using oncology electronic health records

Stasiw, A, Falk, S, Garapati, S, Sridharma, S, Mendelsohn, D, Lakhtakia, S, Rech, A, Oldridge, D, Adamson, BJS, Chen, R

May 2020

Abstract

ISPOR Annual Meeting

Flatiron-authored

May 2020

Abstract

AACR Annual Meeting

Flatiron-authored

Identification of genomic alterations related to treatment progression in RWD

Chaudhary, N, Luhn, P, Jansen, G, Metcalfe, C, Hafner, M

May 2020

Abstract

AACR Annual Meeting

May 2020

Abstract

AACR Annual Meeting

May 2020

Abstract

AACR Annual Meeting

Characterization and potential therapeutic implications of SMARCA4 variants revealed by targeted exome-sequencing of 131668 cancer patients

Fernando, TM, Piskol, R, Bainer, R, Sokol, ES, Trabucco, SE, Zhang, Q, Trinh, H, Maund, SL, Kschonsak, M, Chaudhuri, S, Modrusan, Z, Januario, T, Modrusan, Z, Yauch, RL

May 2020

Abstract

Nature Communications

May 2020

Manuscript

Future Oncology

Characteristics and outcomes of real-world patients with microsatellite instability-high solid tumors treated with pembrolizumab monotherapy after FDA approval

Snow, T, Swaminathan, A, Snider, J, Schrock, AB, Li, G, Alexander, BM, Singal, G, Castellanos, EH, McCusker, M

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

Association of BRCA alteration type with real-world outcomes to PARP inhibitors in patients with metastatic castrate-resistant prostate cancer

Antonarakis, ES, Madison, RW, Snider, J, Snow, T, Sokol, ES, Chung, JH, McCusker, M, Singal, G, Alexander, BM, Castellanos, EH, Venstrom, JM, Schrock, AB, Ross, JS

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

An automated EHR-based tool for identification of patients with metastatic disease to facilitate clinical trial patient ascertainment

Kirshner, J, Cohn, K, Dunder, Steven, Donahue, K, Richey, MM, Larson, PD, Sutton, LM, Siu, E, Donegan, J, Chen, Z, Nightingale, C, Hamrick, HJ

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

Use of real-world data to understand barriers to interventional clinical trial enrollment in community oncology clinics

Blakely, J, Gordon, L, Schwartzberg, L, Gutman, J, Adamson, BJS, Bourla, AB, Meropol, NJ, Ramsey, SD, Green, RJ

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

A multi-stakeholder platform to prospectively link longitudinal real-world clinico-genomic, imaging, and outcomes data for patients with metastatic lung cancer

Lu, MW, Walia, G, Schulze, K, Doral, MY, Maund, SL, Gaffey, S, Cabili, MN, Bourla, AB, Green, RJ, Santos, EC, Herbst, RS, Chiang, AC, Schwartzberg, L

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

The adoption of immune checkpoint inhibitors and patterns of care at the end of life

Riaz, F, Gan, G, Li, F, Davidoff, AJ, Adelson, KB, Presley, CJ, Adamson, BJS, Shaw, P, Parikh, RB, Mamtani, R, Gross, CP

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

Real-world outcomes for advanced non-small cell lung cancer patients with EGFR exon 19 deletions stratified by deletion size

Ou, SI, Madison, RW, Snow, T, Snider, J, McCusker, M, Singal, G, Alexander, BM, Venstrom, JM, Castellanos, EH, Schrock, AB

May 2020

Abstract

ASCO Annual Meeting

Flatiron-authored

May 2020

Abstract

ASCO Annual Meeting

May 2020

Abstract

ASCO Annual Meeting

May 2020

Abstract

ASCO Annual Meeting

May 2020

Abstract

ASCO Annual Meeting