Association between FDA label restriction and immunotherapy and chemotherapy use in bladder cancer

Parikh RB, Adamson BJS, Khozin S, Galsky MD, Baxi SS, Cohen A, Mamtani R

September 2019

Manuscript

JAMA

Flatiron-authored

Developing real-world comparators for clinical trials in chemotherapy-refractory patients with gastric cancer or gastroesophageal junction cancer

Chau I, Le DT, Ott PA, Korytowsky B, Le H, Le TK, Zhang Y, Sanchez T, Maglinte GA, Laurie M, Abraham P, Patel D, Shangguan T

September 2019

Manuscript

Gastric Cancer

Cost effectiveness of PD-L1-based test-and-treat strategy with pembrolizumab as the first-line treatment for metastatic NSCLC in Hong Kong

Loong HH, Wong CKH, Leung LKS, Dhankhar P, Insinga RP, Chandwani S, Hsu DC, Lee MYK, Huang M, Pellissier J, Rai A, Achra M, Tan SC

September 2019

Manuscript

Pharmacoeconomics Open

Validation of diagnosis codes to identify side of colon in an electronic health record registry

Luhn P, Kuk D, Carrigan G, Nussbaum N, Sorg R, Rohrer R, Tucker MG, Arnieri B, Taylor MD, Meropol NJ

August 2019

Manuscript

BMC Medical Research Methodology

Flatiron-authored

Characterizing the feasibility and performance of real-world tumor progression end points and their association with overall survival in a large advanced non–small-cell lung cancer data set

Griffith SD, Miksad RA, Calkins G, You P, Lipitz NG, Bourla AB, Williams E, George DJ, Schrag D, Khozin S, Capra WB, Taylor MD, Abernethy AP

August 2019

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored

Comparative effectiveness of first-line nab-paclitaxel versus paclitaxel monotherapy in triple-negative breast cancer

Luhn P, Chui SY, Hsieh AF, Yi J, Mecke A, Bajaj PS, Hasnain W, Falgas A, Ton TG, Kurian AW

August 2019

Manuscript

Journal of Comparative Effectiveness Research

Real‐world progression, treatment, and survival outcomes during rapid adoption of immunotherapy for advanced non–small cell lung cancer

Khozin S, Miksad RA, Adami J, Boyd M, Brown NR, Gossai A, Kaganman I, Kuk D, Rockland JM, Pazdur R, Torres AZ, Zhi J, Abernethy AP

August 2019

Manuscript

Cancer

Flatiron-authored

July 2019

Manuscript

Journal of Clinical Oncology

Effectiveness of first-line immune checkpoint blockade versus carboplatin-based chemotherapy for metastatic urothelial cancer

Feld E, Harton J, Meropol NJ, Adamson BJS, Cohen A, Parikh RB, Galsky MD, Narayan V, Christodouleas J, Vaughn DJ, Hubbard RA, Mamtani R

July 2019

Manuscript

European Urology

Flatiron-authored

July 2019

Manuscript

Clinical Pharmacology and Therapeutics

An exploratory analysis of real-world end points for assessing outcomes among immunotherapy-treated patients with advanced non-small-cell lung cancer

Stewart M, Norden AD, Dreyer N, Henk HJ, Abernethy AP, Chrischilles E, Kushi L, Mansfield AS, Khozin S, Sharon E, Arunajadai S, Carnahan R, Christian JB, Miksad RA, Sakoda LC, Torres AZ, Valice E, Allen J

July 2019

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored

July 2019

Manuscript

Medicine

June 2019

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored

ISPOR, the FDA, and the evolving regulatory science of medical device products

O'Neill T, Miksad R, Miller D, Maloney L, John A, Hiller C, Hornberger, J

June 2019

Manuscript

Value in Health

Flatiron-authored

June 2019

Manuscript

Immunotherapy

May 2019

Manuscript

Advances in Therapy

Flatiron-authored

May 2019

Manuscript

JNCCN

Flatiron-authored

May 2019

Manuscript

Clinical Pharmacology and Therapeutics

Flatiron-authored

May 2019

Manuscript

Cancer Control

April 2019

Manuscript

Clinical Lung Cancer

Association of Patient Characteristics and Tumor Genomics With Clinical Outcomes Among Patients With Non–Small Cell Lung Cancer Using a Clinicogenomic Database

Singal G, Miller PG, Agarwala V, Li G, Kaushik G, Backenroth D, Gossai A, Frampton GM, Torres AZ, Lehnert E, Bourque D, O’Connell C, Bowser B, Caron T, Baydur E, Seidl-Rathkopf K, Ivanov I, Alpha-Cobb G, Guria A, He J, Frank S, Nunnally A, Bailey M, Jaskiw A, Feuchtbaum D, Nussbaum N, Abernethy AP, Miller VA.

April 2019

Manuscript

JAMA

Flatiron-authored

April 2019

Manuscript

Cancer Epidemiology

Trends in Checkpoint Inhibitor Therapy for Advanced Urothelial Cell Carcinoma at the End of Life: Insights from Real-World Practice

Parikh RB, Galsky MD, Gyawali B, Riaz F, Kaufmann T, Cohen AB, Adamson BJS, Gross CP, Meropol NJ, Mamtani R.

April 2019

Manuscript

The Oncologist

Flatiron-authored

April 2019

Manuscript

Perspectives in Health Information Management

Implementing an Electronic End-of-Life Chemotherapy Utilization Measure

Kraut J, Mooney K, Sweetenham JW, Page RD, Adelson K, Agarwala V, Fessele KL, Hamrick HJ, Kaganman I, Martineau J, Abernethy AP, and Meropol NJ

March 2019

Manuscript

Journal of Oncology Practice

Flatiron-authored

An evaluation of the impact of missing deaths on overall survival analyses of advanced non–small cell lung cancer patients conducted in an electronic health records database

Carrigan, G, Whipple, S, Taylor, MD, Torres, AZ, Gossai, A, Arnieri, B, Tucker, M, Hofmeister, PP, Lambert, P, Griffith, SD, Capra, WB

March 2019

Manuscript

Pharmacoepidemiology & Drug Safety

Flatiron-authored

March 2019

Manuscript

Frontiers in Oncology

Flatiron-authored

Increased risk of brain metastases in ovarian cancer patients with BRCA mutations

Ratner E, Bala M, Louie-Gao M, Aydin E, Hazard S, Brastianos PK

March 2019

Manuscript

Gynecologic Oncology

February 2019

Manuscript

Future Oncology

Disparities in broad-based genomic sequencing for patients with advanced non-small cell lung cancer

Riaz, F, Presley, CJ, Chiang, AC, Longtine, JA, Soulos, PR, Adelson, KB, Herbst, RS, Nussbaum, NC, Sorg, RA, Abernethy, AP, Agarwala, V, Gross, CP

February 2019

Manuscript

Journal of Geriatric Oncology

Flatiron-authored

January 2019

Manuscript

Advances in Therapy

January 2019

Manuscript

International Journal of Colorectal Disease

January 2019

Manuscript

PLoS One

Real-World Outcomes of Patients with Metastatic Non-Small Cell Lung Cancer Treated with Programmed Cell Death Protein 1 Inhibitors in the Year Following U.S. Regulatory Approval

Khozin S, Carson KR, Zhi J, Tucker M, Lee SE, Light DE, Curtis MD, Bralic M, Kaganman I, Gossai A, Hofmeister PP, Torres AZ, Miksad RA, Blumenthal GM, Pazdur R, Abernethy AP

December 2018

Manuscript

The Oncologist

Flatiron-authored

December 2018

Manuscript

Current Medical Research and Opinion

Flatiron-authored

Initiation and interruption in intravenous bisphosphonate therapy among patients with multiple myeloma in the United States

McGrath LJ, Hernandez RK, Overman R, Reams D, Liede A, Brookhart MA, O’Donnell E, Leah J

December 2018

Manuscript

Cancer Medicine

November 2018

Manuscript

Current Medical Research and Opinion

ALK Testing Trends and Patterns Among Community Practices in the United States

Illei P, Wong W, Wu N, Chu L, Gupta R, Schulze K, Gubens M

October 2018

Manuscript

JCO Precision Oncology

Accelerating Anticancer Drug Development — Opportunities and Trade-offs

Nass S, Rothenberg M, Pentz R, Hricak H, Abernethy AP, Anderson K, Gee A, Harvey RD, Piantadosi S, Bertagnolli M, Schrag D, Schilsky R

October 2018

Manuscript

Nature Reviews Clinical Oncology

Flatiron-authored

September 2018

Manuscript

Future Medicine

Flatiron-authored

September 2018

Manuscript

OncoImmunology

Flatiron-authored

Association of Broad-Based Genomic Sequencing With Survival Among Patients With Advanced Non-Small Cell Lung Cancer in the Community Setting

Presley C, Tang D, Soulos P, Chiang A, Longtine J, Adelson K, Herbst R, Zhu W, Nussbaum N, Sorg R, Agarwala V, Abernethy AP, Gross C

August 2018

Manuscript

JAMA

Flatiron-authored

August 2018

Manuscript

Supportive Care in Cancer

Disparities in the use of programmed death 1 immune checkpoint inhibitors

O’Connor, JM, Seidl-Rathkopf, K, Torres, AZ, You, P, Carson, KR, Ross, JS, Gross, CP

July 2018

Manuscript

The Oncologist

Flatiron-authored

Comparative Effectiveness from a Single-Arm Trial and Real-World Data: Alectinib versus Ceritinib

Davies J, Martinec M, Delmar P, Coudert M, Bordogna W, Golding S, Reynaldo M, Crane G

June 2018

Manuscript

Future Medicine

Development and Validation of a High‐Quality Composite Real‐World Mortality Endpoint

Curtis MD, Griffith S, Tucker M, Taylor M, Capra W, Carrigan G, Holzman B, Torres AZ, You P, Arnieri B, Abernethy AP

May 2018

Manuscript

Health Services Research

Flatiron-authored

Speed of Adoption of Immune Checkpoint Inhibitors of Programmed Cell Death 1 Protein and Comparison of Patient Ages in Clinical Practice vs Pivotal Clinical Trials

O’Connor J, Fessele K, Steiner J, Seidl-Rathkopf K, Carson K, Nussbaum N, Yin E, Adelson K, Presley C, Chiang A, Ross J, Abernethy AP, Gross C

May 2018

Manuscript

JAMA Oncology

Flatiron-authored

Real-World Evidence In Support Of Precision Medicine: Clinico-Genomic Cancer Data As A Case Study

Agarwala V, Khozin S, Singal G, O'Connell C, Kuk D, Li G, Gossai A, Miller V, Abernethy AP

May 2018

Manuscript

Health Affairs

Flatiron-authored

February 2018

Manuscript

Clinical Therapeutics

Flatiron-authored

Characteristics of Real-World Metastatic Non-Small Cell Lung Cancer Patients Treated with Nivolumab and Pembrolizumab During the Year Following Approval

Khozin S, Abernethy AP, Nussbaum N, Zhi J, Curtis MD, Tucker M, Lee S, Light D, Gossai A, Sorg R, Torres AZ, Patel P, Blumenthal G, Pazdur R

January 2018

Manuscript

The Oncologist

Flatiron-authored

Treatment Dynamics of Bone-Targeting Agents Among Men with Bone Metastases from Prostate Cancer in the United States

Butler A, Cetin K, Hernandez RK, Reams D, Overman R, Kim J, Hirsch B, Abernethy AP, Liede A, Brookhart A

January 2018

Manuscript

Pharmacoepidemiology & Drug Safety

Flatiron-authored

December 2017

Manuscript

Clinical Pharmacology and Therapeutics

Flatiron-authored

Use of Electronic Health Record Data for Quality Reporting

Abernethy AP, Gippetti J, Parulkar R, Revol C

August 2017

Manuscript

Journal of Oncology Practice

Flatiron-authored

June 2017

Manuscript

PLoS One

Flatiron-authored

March 2016

Manuscript

Clinical Lung Cancer

Flatiron-authored

March 2016

Manuscript

Future Oncology

Flatiron-authored

November 2015

Manuscript

Clinical Epidemiology

Flatiron-authored