Real-world evidence at ASCO21: Explore new research here

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December 2021

Abstract

American Society of Hematology Annual Meeting

Flatiron-authored

Racial disparities in telemedicine uptake during the COVID-19 pandemic among patients with hematologic malignancies in the United States

Neparidze, N, Lau, K, Wang, X, Davidoff, AJ, Huntington, SF, Jamy, O, Calip, GS, Shah, H, Stephens, D, Miksad, RA, Parikh, RB, Takvorian, SU, Goyal, G, Seymour, E

December 2021

Abstract

American Society of Hematology Annual Meeting

Flatiron-authored

Impact of the COVID-19 pandemic on in-person visit rates among patients with hematologic malignancies in the United States

Goyal, G, Lau, K, Wang, X, Davidoff, AJ, Huntington, SF, Jamy, O, Stephens, D, Miksad, RA, Parikh, RB, Takvorian, SU, Neparidze, N, Seymour, E

December 2021

Abstract

American Society of Hematology Annual Meeting

Flatiron-authored

December 2021

Manuscript

Cancer

Flatiron-authored

Generating Real-World External Comparators (rwECs) for Randomized Clinical Trials (RCTs) in Metastatic Breast Cancer (mBC) using Electronic Health Records (EHRs)

Amiri-Kordestani, L, Gao, X, Baxi, SS, Bloomquist, E, Bryan, J, Howie, L, Keane, C, Kluetz, P, Osgood, C, Paliwal, P, Rivera, DR, Roose, JP, Schneider, J, Ssingh, H, Tang, S, Zhang, L, Beaver, J

December 2021

Abstract

San Antonio Breast Cancer Symposium

Flatiron-authored

Patient Safety Usability Testing in Electronic Health Record Feature Development

Speicher, S, Wynn, F, Ritter, K, Wade, N, Kumar, A

December 2021

Abstract

IHI Forum

Flatiron-authored

Patient Safety Impact Assessment (PSIA): A Way to Assess Potential Safety Implications of Software Features Prior to Development and Product Launch

Speicher, S, Wynn, F, Wade, N

December 2021

Abstract

IHI Forum

Flatiron-authored

December 2021

Abstract

EU ISPOR

Flatiron-authored

November 2021

Manuscript

Digital Health

Flatiron-authored

Real-world data of palbociclib in combination with endocrine therapy for the treatment of metastatic breast cancer in men

Kraus, AL, Yu-Kite, M, Mardekian, J, Cotter, MJ, Kim, S, Decembrino, J, Snow, T, Carson, KR, Rockland, JM, Gossai, A, Wilner, KD, Wang, D, Bartlett, CH, Oharu, N, Schnell, P, VanArsdale, T, Lu, D, Tursi, J

October 2021

Manuscript

Clinical Pharmacology and Therapeutics

Flatiron-authored

Real-world Overall Survival Using Oncology Electronic Health Record Data: Friends of Cancer Research Pilot

Lasiter, L, Tymejczyk, O, Garrett-Mayer, E, Baxi, SS, Belli, AJ, Boyd, M, Christian, JB, Cohen, AB, Espirito, JL, Hansen, E, Sweetnam, C, Robert, NJ, Small, M, Stewart, M, Izano, MA, Wagner, J, Natanzon, Y, Rivera, DR, Allen, J

October 2021

Manuscript

Clinical Pharmacology and Therapeutics

Flatiron-authored

October 2021

Manuscript

Value in Health

Flatiron-authored

September 2021

Abstract

ASCO Quality Care Symposium

Flatiron-authored

Trends in Diagnosis and Treatment of Early Breast Cancer (eBC) in the United States (US) During the COVID-19 Era

Ackerman, B, Keane, C, Beaver, J, Kluetz, P, Rivera, DR, Paliwal, P, Ssingh, H, Mpofu, P, Amiri-Kordestani, L, Baxi, SS

September 2021

Abstract

ASCO Quality Care Symposium

Flatiron-authored

Implementation of an EHR-embedded decision support tool in community oncology practices

Maniago, R, Richey, S, DeVincenzo, S, Jou, S, Linzmayer, R, Donegan, J, Calip, GS, Altomare, I

September 2021

Abstract

ASCO Quality Care Symposium

Flatiron-authored

September 2021

Abstract

ESMO Annual Congress

Flatiron-authored

Real-world outcomes of hormone receptor-positive (HR+) HER2-negative (HER2-) metastatic breast cancer (mBC) with high tumor mutational burden (hTMB) treated with immune checkpoint inhibitors (ICI)

Chumsri, S, Sammons, S, Alder, L, Sokol, ES, Danziger, NA, Raskina, K, Schrock, AB, Venstrom, JM, Snow, T, Castellanos, EH, Ochuonyo, E, Snider, JW, MGregor, K

September 2021

Abstract

ESMO Annual Congress

Flatiron-authored

Real-world outcomes of hormone receptor-positive (HR+) HER2-negative (HER2-) metastatic breast cancer (mBC) with high tumor mutational burden (hTMB) treated with immune checkpoint inhibitors (ICI)

Chumsri, S, Sammons, S, Alder, L, Sokol, ES, Danziger, NA, Raskina, K, Schrock, AB, Venstrom, JM, Snow, T, Castellanos, EH, Ochuonyo, E, Snider, JW, MGregor, K

September 2021

Abstract

ESMO Annual Congress

Flatiron-authored

September 2021

Abstract

ESMO Annual Congress

Flatiron-authored

September 2021

Manuscript

Cancer

Flatiron-authored

August 2021

Manuscript

JNCI Cancer Spectrum

Telemedicine use among U.S. cancer patients during the COVID-19 pandemic

Chen, L, Avile, CF, Kundu, P, Cohen, AB, Webster, A, Rohrer, R, Taylor, M

August 2021

Abstract

International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE)

Flatiron-authored

August 2021

Manuscript

Future Oncology

Flatiron-authored

August 2021

Manuscript

Targeted Oncology

ACA Medicaid expansion association with racial disparity reductions in timely cancer treatment

Adamson, BJS, Cohen, AB, Gross, CP, Estévez, M, Magee, K, Williams, ER, Meropol, NJ, Davidoff, AJ

July 2021

Abstract

American Journal of Managed Care (AJMC)

Flatiron-authored

July 2021

Manuscript

JAMA Open

Flatiron-authored

July 2021

Manuscript

Pharmacoepidemiology & Drug Safety

Flatiron-authored

An automated electronic health record-based tool for identification of patients with metastatic disease to facilitate clinical trial patient ascertainment

Kirshner, J, Cohn, K, Dunder, S, Donahue, K, Richey, MM, Larson, PD, Sutton, LM, Siu, E, Donegan, J, Chen, Z, Nightingale, C, Hamrick, HJ

July 2021

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored

Emulating control arms for cancer clinical trials using external cohorts created from electronic health record-derived real-world data

Tan, K, Bryan, J, Segal, BD, Bellomo, L, Nussbaum, NC, Tucker, MG, Torres, AZ, Bennette, CS, Capra, WB, Curtis, MD, Miksad, RA

July 2021

Manuscript

Clinical Pharmacology and Therapeutics

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Comparing phase 3 “go” decisions (Ph3-GO) between single arm trials with real-world external control (SAT+rwEC) versus randomized phase 2 trials (rPh2)

Hobbs, B, Ton, TGN, Li, X, Hong, DS, Hubbard, RA, Mangat, PK, Capra, WB, Kong, S, Pang, H, Samant, MK, Segal, BD, Garrett-Mayer, E

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Evaluating real-world overall survival (rwOS) across oncology data sources: Friends of Cancer Research non-small cell lung cancer pilot study

Lasiter, L, Baxi, SS, Belli, AJ, Boyd, M, Christian, JB, Cohen, AB, Espirito, JL, Garrett-Mayer, E, Hansen, E, Izano, MA, Natanzon, Y, Rivera, DR, Robert, NJ, Small, M, Sweetnam, C, Tymejczyk, O, Wagner, J, Allen, J

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Plasma circulating tumor DNA (ctDNA) fraction and real-world overall survival (rwOS) in metastatic castration resistant prostate cancer (mCRPC)

Graf, RP, Li, G, Madison, RW, Schrock, AB, Huang, RSP, Oxnard, G, Venstrom, JM, Castellanos, EH, Snow, T, Swaminathan, A

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

An automated EHR-based tool to improve patient identification for biomarker-driven trials

Lakhanpal, S, Hawkins, K, Dunder, Steven, Donahue, K, Richey, MM, Liu, E, Brachfeld, A, Shelley, A, Sutton, LM, Green, D, Siu, E, Hamrick, HJ

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Clinical characteristics, treatment patterns, and overall survival of real-world patients with idiopathic multicentric Castleman disease

Cohen, AB, Swaminathan, A, Wang, X, Zamora, S, Repucci, MA, Kelly, J, Hannan, M, Sepler, D, Sridharma, S, Orlando, A, Leybovich, B, Fajgenbaum, D

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Time to treatment initiation for patients with advanced cancer documented during the COVID-19 pandemic

Takvorian, SU, Parikh, RB, Vader, D, Wileyto, EP, Clark, AS, Lee, DJ, Goyal, G, Rocque, GB, Dotan, E, Geynisman, DM, Phull, P, Spiess, PE, Kim, RY, Davidoff, AJ, Gross, CP, Miksad, RA, Calip, GS, Shulman, L, Mamtani, R, Hubbard, RA

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

ERBB2 copy number (CN) as a quantitative biomarker for real-world (RW) outcomes to anti-HER2 therapy in advanced gastroesophageal adenocarcinoma (adv GEA)

Klempner SJ, Zhang, L, Graf, RP, Madison, RW, Snider, JW, Cho-Phan, C, Castellanos, EH, Li, G, Nimeiri, H, Oxnard, G, Venstrom, JM, MGregor, K, Schrock, AB

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Analysis of real world data (RWD) for metastatic breast cancer (mBC) patients (pts) without germline BRCA (gBRCA) alterations treated with PARP inhibitors (PARPi)

Tung, N, Madison, RW, Pavlick, D, Sokol, ES, Snow, T, Sondhi, A, Frampton, GM, Venstrom, JM, Castellanos, EH, Schrock, AB, MGregor, K

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

June 2021

Abstract

ASCO Annual Meeting

June 2021

Abstract

ASCO Annual Meeting

June 2021

Abstract

ASCO Annual Meeting

Role of cytoreductive nephrectomy in metastatic renal cell carcinoma

Ghatalia, P, Handorf, E, Deng, M, Zibleman, M, Abbosh, P, Anari, F, Greenberg, RE, Viterbo, R, Chen, D, Smaldone, MC, Kutikov, A, Geynisman, DM, Uzzo, R

June 2021

Abstract

ASCO Annual Meeting

Molecular, immunologic, and clinicodemographic landscape of MYC-amplified (MYCamp) advanced prostate cancer (PCa)

Mahal, BA, Zhang, L, Alshalalfa, M, Graf, RP, Tukachinsky, H, Huang, RSP, McGregor, K, Schrock, AB, Venstrom, JM

June 2021

Abstract

ASCO Annual Meeting

May 2021

Manuscript

Future Oncology

Flatiron-authored

Immune checkpoint inhibitor uptake in real-world patients with malignant pleural mesothelioma

Kim, RY, Mitra, N, Bagley, SJ, Marmarelis, ME, Haas, AR, Rendle, KA, Vachani, A

May 2021

Manuscript

JTO Clinical and Research Reports

May 2021

Manuscript

Health Services Research

Flatiron-authored