Real-world evidence at ASCO21: Explore new research here

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Telemedicine use among U.S. cancer patients during the COVID-19 pandemic

Chen, L, Avile, CF, Kundu, P, Cohen, AB, Webster, A, Rohrer, R, Taylor, M

August 2021

Abstract

International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE)

Flatiron-authored

August 2021

Manuscript

Future Oncology

Flatiron-authored

August 2021

Manuscript

Targeted Oncology

ACA Medicaid expansion association with racial disparity reductions in timely cancer treatment

Adamson, BJS, Cohen, AB, Gross, CP, Estévez, M, Magee, K, Williams, ER, Meropol, NJ, Davidoff, AJ

July 2021

Abstract

American Journal of Managed Care (AJMC)

Flatiron-authored

July 2021

Manuscript

JAMA Open

Flatiron-authored

July 2021

Manuscript

Pharmacoepidemiology & Drug Safety

Flatiron-authored

An automated electronic health record-based tool for identification of patients with metastatic disease to facilitate clinical trial patient ascertainment

Kirshner, J, Cohn, K, Dunder, S, Donahue, K, Richey, MM, Larson, PD, Sutton, LM, Siu, E, Donegan, J, Chen, Z, Nightingale, C, Hamrick, HJ

July 2021

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored

Emulating control arms for cancer clinical trials using external cohorts created from electronic health record-derived real-world data

Tan, K, Bryan, J, Segal, BD, Bellomo, L, Nussbaum, NC, Tucker, MG, Torres, AZ, Bennette, CS, Capra, WB, Curtis, MD, Miksad, RA

July 2021

Manuscript

Clinical Pharmacology and Therapeutics

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Comparing phase 3 “go” decisions (Ph3-GO) between single arm trials with real-world external control (SAT+rwEC) versus randomized phase 2 trials (rPh2)

Hobbs, B, Ton, TGN, Li, X, Hong, DS, Hubbard, RA, Mangat, PK, Capra, WB, Kong, S, Pang, H, Samant, MK, Segal, BD, Garrett-Mayer, E

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Evaluating real-world overall survival (rwOS) across oncology data sources: Friends of Cancer Research non-small cell lung cancer pilot study

Lasiter, L, Baxi, SS, Belli, AJ, Boyd, M, Christian, JB, Cohen, AB, Espirito, JL, Garrett-Mayer, E, Hansen, E, Izano, MA, Natanzon, Y, Rivera, DR, Robert, NJ, Small, M, Sweetnam, C, Tymejczyk, O, Wagner, J, Allen, J

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Plasma circulating tumor DNA (ctDNA) fraction and real-world overall survival (rwOS) in metastatic castration resistant prostate cancer (mCRPC)

Graf, RP, Li, G, Madison, RW, Schrock, AB, Huang, RSP, Oxnard, G, Venstrom, JM, Castellanos, EH, Snow, T, Swaminathan, A

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

An automated EHR-based tool to improve patient identification for biomarker-driven trials

Lakhanpal, S, Hawkins, K, Dunder, Steven, Donahue, K, Richey, MM, Liu, E, Brachfeld, A, Shelley, A, Sutton, LM, Green, D, Siu, E, Hamrick, HJ

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Clinical characteristics, treatment patterns, and overall survival of real-world patients with idiopathic multicentric Castleman disease

Cohen, AB, Swaminathan, A, Wang, X, Zamora, S, Repucci, MA, Kelly, J, Hannan, M, Sepler, D, Sridharma, S, Orlando, A, Leybovich, B, Fajgenbaum, D

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Time to treatment initiation for patients with advanced cancer documented during the COVID-19 pandemic

Takvorian, SU, Parikh, RB, Vader, D, Wileyto, EP, Clark, AS, Lee, DJ, Goyal, G, Rocque, GB, Dotan, E, Geynisman, DM, Phull, P, Spiess, PE, Kim, RY, Davidoff, AJ, Gross, CP, Miksad, RA, Calip, GS, Shulman, L, Mamtani, R, Hubbard, RA

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

ERBB2 copy number (CN) as a quantitative biomarker for real-world (RW) outcomes to anti-HER2 therapy in advanced gastroesophageal adenocarcinoma (adv GEA)

Klempner SJ, Zhang, L, Graf, RP, Madison, RW, Snider, JW, Cho-Phan, C, Castellanos, EH, Li, G, Nimeiri, H, Oxnard, G, Venstrom, JM, MGregor, K, Schrock, AB

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

Analysis of real world data (RWD) for metastatic breast cancer (mBC) patients (pts) without germline BRCA (gBRCA) alterations treated with PARP inhibitors (PARPi)

Tung, N, Madison, RW, Pavlick, D, Sokol, ES, Snow, T, Sondhi, A, Frampton, GM, Venstrom, JM, Castellanos, EH, Schrock, AB, MGregor, K

June 2021

Abstract

ASCO Annual Meeting

Flatiron-authored

June 2021

Abstract

ASCO Annual Meeting

June 2021

Abstract

ASCO Annual Meeting

June 2021

Abstract

ASCO Annual Meeting

June 2021

Abstract

ASCO Annual Meeting

Role of cytoreductive nephrectomy in metastatic renal cell carcinoma

Ghatalia, P, Handorf, E, Deng, M, Zibleman, M, Abbosh, P, Anari, F, Greenberg, RE, Viterbo, R, Chen, D, Smaldone, MC, Kutikov, A, Geynisman, DM, Uzzo, R

June 2021

Abstract

ASCO Annual Meeting

Molecular, immunologic, and clinicodemographic landscape of MYC-amplified (MYCamp) advanced prostate cancer (PCa)

Mahal, BA, Zhang, L, Alshalalfa, M, Graf, RP, Tukachinsky, H, Huang, RSP, McGregor, K, Schrock, AB, Venstrom, JM

June 2021

Abstract

ASCO Annual Meeting

May 2021

Manuscript

Future Oncology

Flatiron-authored

Immune checkpoint inhibitor uptake in real-world patients with malignant pleural mesothelioma

Kim, RY, Mitra, N, Bagley, SJ, Marmarelis, ME, Haas, AR, Rendle, KA, Vachani, A

May 2021

Manuscript

JTO Clinical and Research Reports

May 2021

Manuscript

Health Services Research

Flatiron-authored

May 2021

Abstract

ISPOR Annual Meeting

Flatiron-authored

Quantifying bias in Flatiron ML-extracted variables for inference in clinical oncology

Lee, J, Estévez, M, Segal, BD, Sondhi, A, Cohen, AB, Cherng, S

May 2021

Abstract

ISPOR Annual Meeting

Flatiron-authored

May 2021

Abstract

ISPOR Annual Meeting

Flatiron-authored

Enhanced cost-effectiveness analysis using EHR data for real-world value

Swaminathan, A, Xu, C, Zhang, S, Du, K, Siu, E, Kalesinskas, L, Lite, S, Song, Y, Snider, JW, Schwemm, A, Bargo, D, Adamson, BJS

May 2021

Abstract

ISPOR Annual Meeting

Flatiron-authored

Can early US adoption of cancer drugs inform HTA decision making?

Jonsson, P, Mpofu, P, Copeland, A, Kent, S, Groves, B, Bargo, D, Ramsey, SD, Baxi, SS, Adamson, BJS

May 2021

Abstract

ISPOR Annual Meeting

Flatiron-authored

Real-world treatment patterns and outcomes of abemaciclib for the treatment of HR+, HER2-metastatic breast cancer

Carter, GC, Sheffield, KM, Gossai, A, Huang, Y, Zhu, YE, Bowman, L, Smyth, EN, Mathur, R, Cohen, AB, Rasmussen, E, Balakrishna, S, Guimaraes, CM, Rybowski, S, Seidman, AD

May 2021

Manuscript

Current Medical Research and Opinion

Flatiron-authored

Patient with lobular carcinoma of the breast and activating AKT1 E17K variant

Trivedi, H, Hamdani, O, Thomas, B, Richard, J, Shah, K, Raskina, K, Zhang, L, Madigan, A, Fox, M, Wander, S, Frigault, M, Alexander, BM, Srkalovic, G

April 2021

Manuscript

Acta Medica Academia

April 2021

Manuscript

Scientific Reports

TRK fusion cancer: patient characteristics and survival analysis in the real-world setting

Bazhenova, L, Lokker, A, Snider, JW, Castellanos, EH, Fisher, V, Fellous, M, Nanda, S, Zong, J, Keating, K, Jiao, X

April 2021

Manuscript

Targeted Oncology

Flatiron-authored

Artificial intelligence for prognostic scores in oncology: a benchmarking study

Loureiro, H, Becker, T, Bauer-Mehren, A, Ahmidi, N, Weberpals, J

April 2021

Manuscript

Frontiers in Artificial Intelligence

April 2021

Manuscript

JAMA Oncology

Treatment patterns in patients with metastatic non-small-cell lung cancer in the era of immunotherapy

Stenehjem, D, Lubinga, S, Betts, KA, Tang, W, Jenkins, M, Yuan, Y, Hartman, J, Rao, S, Lam, J, Waterhouse, D

April 2021

Manuscript

Future Oncology

April 2021

Abstract

AACR Annual Meeting

April 2021

Abstract

AACR Annual Meeting

Immune checkpoint inhibitor therapy for metastatic colorectal cancer: real-world practice patterns and predictors of overall survival

Bari, S, Matejcic, M, Kim, R, Xie, H, Carballido, E, Sahin, I, Powers, B, Felder, S, Schmit, SL

April 2021

Abstract

AACR Annual Meeting

April 2021

Abstract

AACR Annual Meeting

Changes over time in real-world next-generation sequencing test use in patients with advanced non-small cell lung cancer

Swaminathan, A, Stergiopoulos, S, Snider, JW, Fisher, V, Castellanos, EH, Snow, T, Cho-Phan, C, Comment, L, Cunningham, R, McCusker, M

April 2021

Abstract

AACR Annual Meeting

Flatiron-authored

Comprehensive genomic profiling in breast cancer: patterns and results from a clinico-genomic database

Rody, A, Chaudhary, N, Craggs, C, Debiasi, M, Erb, G, Fisher, V, McCusker, M, Snow, T, Losada, MV, Luhn, P

April 2021

Abstract

AACR Annual Meeting

Flatiron-authored

Evaluating oncology trial eligibility criteria using real-world data and AI

Liu, R, Rizzo, S, Whipple, S, Pal, N, Pineda, AL, Lu, MW, Arnieri, B, Lu, Y, Capra, WB, Copping, R, Zou, J

April 2021

Manuscript

Nature

Adherence to NCCN ALK testing guidelines for patients with advanced non‐small cell lung cancer in US community medical centers

Bernicker, E, Xiao, Y, Abraham, A, Yang, B, Croix, D, Redpath, S, Engstrom-Melnyk, J, Shah, RA, Madala, J, Allen, TC

April 2021

Manuscript

The Oncologist

Comparative effectiveness of first-line palbociclib plus letrozole versus letrozole alone for HR+/HER2−metastatic breast cancer in US real-world clinical practice

DeMichele, A, Cristofanilli, M, Brufsky, A, Liu, X, Mardekian, J, McRoy, L, Layman, RM, Emir, B, Torres, M, Rugo, HS, Finn, RS

March 2021

Manuscript

Breast Cancer Research