November 2019

Manuscript

Cancer Medicine

October 2019

Abstract

AMCP Nexus

October 2019

Abstract

AMCP Nexus

Technology-enabled clinical trials: Transforming medical evidence generation

Marquis-Gravel, G, Roe, MT, Turakhia, MP, Boden, W, Temple, R, Sharma, A, Hirshberg, B, Slater, P, Craft, N, Stockbridge, N, McDowell, B, Waldstreicher, J, Bourla, AB, Bansilal, S, Wong, JL, Meunier, C, Kassahun, H, Coran, P, Bataille, L, Patrick-Lake, B, Hirsch, BR, Reites, J, Mehta, R, Muse, ED, Chandross, KJ, Silverstein, JC, Silcox, C, Overhage, JM, Califf, RM, Peterson, ED

October 2019

Manuscript

Circulation

Flatiron-authored

October 2019

Abstract

Asian Conference on Pharmacoepidemiology

Comparative-effectiveness of pembrolizumab vs nivolumab for patients with metastatic melanoma

Moser, JC, Wei, G, Colonna, SV, Grossman, KF, Patel, SB, Hyngstrom, JR

October 2019

Abstract

ESMO Annual Congress

October 2019

Abstract

ESMO Annual Congress

Brain metastases, treatment patterns, and outcomes in ROS1-positive NSCLC patients from US oncology community centers

Krebs, MG, Perez, L, Surinach, A, Doebele, RC, Martina, R, Martinec, M, Riehl, T, Meropol, NJ, Wong, WB, Crane, G

October 2019

Abstract

ESMO Annual Congress

Flatiron-authored

Biomarker status as a mediator of age-related overall survival (OS) in advanced non-small cell lung cancer (aNSCLC)

Cohen, AB, Neri, B, Adamson, BJS, Scanlon, CM, Gross, CP, Meropol, NJ, Miksad, RA

October 2019

Abstract

ESMO Annual Congress

Flatiron-authored

September 2019

Abstract

ESMO Annual Congress

September 2019

Abstract

ESMO Annual Congress

September 2019

Abstract

ESMO Annual Congress

Co-occurrence of NTRK fusions with other genomic biomarkers in cancer patients

Jiao, X, Lokker, A, Snider, J, Castellanos, EH, Nanda, S, Fisher, V, Zong, J, Keating, K, Fellous, M

September 2019

Abstract

ESMO Annual Congress

Flatiron-authored

September 2019

Abstract

ESMO Annual Congress

Flatiron-authored

Prevalence and prognostic effect of high tumor mutation burden (TMB-H) across multiple less common solid cancers using a real-world dataset

Backenroth D, Shao C, Li G, Huang L,Pruitt SK, Castellanos EH, Frampton GM, Carson KR, Snow T, Singal G, Fabrizio D, Alexander BM, Jin FJ, Zhou W

September 2019

Abstract

ESMO Annual Congress

Flatiron-authored

September 2019

Abstract

ESMO Annual Congress

Flatiron-authored

Association between FDA label restriction and immunotherapy and chemotherapy use in bladder cancer

Parikh RB, Adamson BJS, Khozin S, Galsky MD, Baxi SS, Cohen A, Mamtani R

September 2019

Manuscript

JAMA

Flatiron-authored

Developing real-world comparators for clinical trials in chemotherapy-refractory patients with gastric cancer or gastroesophageal junction cancer

Chau I, Le DT, Ott PA, Korytowsky B, Le H, Le TK, Zhang Y, Sanchez T, Maglinte GA, Laurie M, Abraham P, Patel D, Shangguan T

September 2019

Manuscript

Gastric Cancer

Real-world evidence of male breast cancer (BC) patients treated with palbociclib (PAL) in combination with endocrine therapy (ET)

Bartlett, CH, Mardekian, J, Yu-Kite, M, Cotter, MJ, Kim, S, Decembrino, J, Snow, T, Carson, KR, Rockland, JM, Kraus, AL, Wilner, KD, Oharu, N, Schnell, P, Lu, D, Tursi, J

September 2019

Abstract

Annual Metastatic Breast Cancer Conference

Flatiron-authored

Cost effectiveness of PD-L1-based test-and-treat strategy with pembrolizumab as the first-line treatment for metastatic NSCLC in Hong Kong

Loong HH, Wong CKH, Leung LKS, Dhankhar P, Insinga RP, Chandwani S, Hsu DC, Lee MYK, Huang M, Pellissier J, Rai A, Achra M, Tan SC

September 2019

Manuscript

Pharmacoeconomics Open

LKB1 mutations in metastatic non-small cell lung cancer (mNSCLC): Prognostic value in the real world

Golozar, A, Collins, J, Fraeman, K, Nordstrom, BL, McEwen, R, Shire, N, Higgs, B

September 2019

Abstract

World Conference on Lung Cancer

Real-world treatment patterns and survival in non-small cell lung cancer patients with EGFR exon 20 insertion mutations

Dersarkissian, M, Bhak, R, Lin, HM, Li, S, Cheng, M, Lax, A, Huang, H, Duh, MS, Ou, S-H

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

New treatment option for ES-SCLC: Patient characteristics and use of an atezolizumab regimen in the real-world setting

McCune, S, Ton, TGN, Whipple, S, Induru, RR, Horn, L, Percent, IJ, Mekhail, T, Goldschmidt, Jr., J, Leal, TA, MacVicar, GR, Braiteh, F, Daniel, DB, Hussein, M, Mansfield, AS, Lam, S, Johnson, A, Morris, S, Spira, A

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

September 2019

Abstract

World Conference on Lung Cancer

BRAF mutations are associated with increased benefit from PD-1/PD-L1 blockade compared with other oncogenic drivers in non-small cell lung cancer

Heymach, JV, Shames, DS, Albacker, LA, Frampton, GM, Alexander, BM, Miller, VA, Glisson, BS, Gibbons, DL, Papadimitrakopoulou, V, Tsao, AS, Lee, J, Swisher, S, Roth, JA, Simon, GS, Rinsurongkawong, W, Barreto, D, Zhang, J, Wu, C-J, Goldberg, ME, Le, X, Elamin, Y, Hu, S, Shen, V, Bara, I, Schulze, K, Montesion, M, Skoulidis, F, Negrão, M

September 2019

Abstract

World Conference on Lung Cancer

Real-world outcomes of advanced NSCLC patients with common and uncommon/complex EGFR mutation profiles

Riely, GJ, Lovly, CM, Messina, CGM, Bienert, S, Alexander, K, Pao, W, Magee, K, Baxi, SS, Doebele, RC

September 2019

Abstract

World Conference on Lung Cancer

Flatiron-authored

September 2019

Abstract

World Conference on Lung Cancer

Flatiron-authored

Real-world characterization of advanced non-small cell lung cancer in never smokers

Kerrigan, KC, Halland, B, Adamson, BJS, Patel, SB, Akerley, WL

September 2019

Abstract

World Conference on Lung Cancer

Flatiron-authored

Retrospective analysis of real-world clinico-genomic data for clinical impact of genomic profiling of CTDNA in NSCLC

Madison, R, Schrock, AB, Gregg, JP, Carson, KR, Castellanos, EH, Singal, G, Miller, VA, Ali, SM, Alexander, BM, Chung, JH

September 2019

Abstract

World Conference on Lung Cancer

Flatiron-authored

Comparative efficacy analysis between entrectinib trial and crizotinib real-world ROS1 fusion-positive (ROS1+) NSCLC patients

Doebele, RC, Perez, L, Trinh, H, Martinec, M, Martina, R, Riehl, T, Krebs, MG, Meropol, NJ, Wong, WB, Crane, G

September 2019

Abstract

World Conference on Lung Cancer

Flatiron-authored

Development of a time to treatment metric across an NCI designated academic health system

Najarian, ML, Shaw, P, Severino, KM, Hamrick, HJ, Adelson, KB, Miksad, RA

September 2019

Abstract

ASCO Quality Care Symposium

Flatiron-authored

August 2019

Abstract

International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE)

August 2019

Abstract

International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE)

August 2019

Abstract

International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE)

August 2019

Abstract

International Conference on Pharmacoepidemiology & Therapeutic Risk Management (ICPE)

Flatiron-authored

Validation of diagnosis codes to identify side of colon in an electronic health record registry

Luhn P, Kuk D, Carrigan G, Nussbaum N, Sorg R, Rohrer R, Tucker MG, Arnieri B, Taylor MD, Meropol NJ

August 2019

Manuscript

BMC Medical Research Methodology

Flatiron-authored

Characterizing the feasibility and performance of real-world tumor progression end points and their association with overall survival in a large advanced non–small-cell lung cancer data set

Griffith SD, Miksad RA, Calkins G, You P, Lipitz NG, Bourla AB, Williams E, George DJ, Schrag D, Khozin S, Capra WB, Taylor MD, Abernethy AP

August 2019

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored

Comparative effectiveness of first-line nab-paclitaxel versus paclitaxel monotherapy in triple-negative breast cancer

Luhn P, Chui SY, Hsieh AF, Yi J, Mecke A, Bajaj PS, Hasnain W, Falgas A, Ton TG, Kurian AW

August 2019

Manuscript

Journal of Comparative Effectiveness Research

Real‐world progression, treatment, and survival outcomes during rapid adoption of immunotherapy for advanced non–small cell lung cancer

Khozin S, Miksad RA, Adami J, Boyd M, Brown NR, Gossai A, Kaganman I, Kuk D, Rockland JM, Pazdur R, Torres AZ, Zhi J, Abernethy AP

August 2019

Manuscript

Cancer

Flatiron-authored

July 2019

Manuscript

Journal of Clinical Oncology

July 2019

Abstract

Joint Statistical Meeting

Flatiron-authored

Effectiveness of first-line immune checkpoint blockade versus carboplatin-based chemotherapy for metastatic urothelial cancer

Feld E, Harton J, Meropol NJ, Adamson BJS, Cohen A, Parikh RB, Galsky MD, Narayan V, Christodouleas J, Vaughn DJ, Hubbard RA, Mamtani R

July 2019

Manuscript

European Urology

Flatiron-authored

July 2019

Manuscript

Clinical Pharmacology and Therapeutics

An exploratory analysis of real-world end points for assessing outcomes among immunotherapy-treated patients with advanced non-small-cell lung cancer

Stewart M, Norden AD, Dreyer N, Henk HJ, Abernethy AP, Chrischilles E, Kushi L, Mansfield AS, Khozin S, Sharon E, Arunajadai S, Carnahan R, Christian JB, Miksad RA, Sakoda LC, Torres AZ, Valice E, Allen J

July 2019

Manuscript

JCO Clinical Cancer Informatics

Flatiron-authored