Spotlight Custom Solutions

Generating real-world evidence

Flatiron has delivered hundreds of spotlight projects in the past 5+ years, with 50+ novel derived variables. Sample variables include:

  • Outcome variables: real-world response, real-world progression, mortality and adverse events
  • Disease and patient characteristics: comorbidities, brain metastases and additional malignancies
  • Drug treatments: detailed dosing and reasons for discontinuation of oral therapies
  • Procedures and tests: treatment for brain/CNS metastases and radiation/surgery data
Download a list of sample variables

Client services

Customers rely on Flatiron for trusted insights and guidance. Flatiron’s team of specialists support customers in their evidence generation needs across the drug lifecycle and can help:

  • Develop briefing books
  • Create Protocols and Statistical Analysis Plans (SAP)
  • Guide cohort selection, analytics, and study design
  • Support regulatory meeting(s)
Learn how Flatiron advances RWE policy

Generate real-world evidence across the life cycle of a drug, pre- and post-launch

Flatiron real-world data has informed key clinical development decisions, supported clinical trial data in regulatory submissions, fulfilled post-marketing commitments, and enabled market access and payer decisions.

Learn more about Flatiron product use cases

Integrated evidence

Enhance data depth and longitudinality with integrated evidence. Spotlight projects can be customized to link patient-level EHR data with genomics, imaging, or claims data.

Linked EHR and Genomics Data

Flatiron Health and Foundation Medicine’s Clinico-Genomics Database (CGDB) for disease-specific and disease-agnostic analyses.

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Linked EHR and Radiology Imaging Data

Datasets that link radiology images (DICOM) with Flatiron’s EHR-derived clinical and outcomes data for disease-specific and disease-agnostic analyses.

Download the fact sheet

Linked EHR and Claims Data 

A real-world linked EHR-Claims data solution that is de-identified and ready for use, unlocking the full patient journey.

Download the fact sheet

Flatiron Spotlight was chosen because it’s fit-for-purpose. You have the right population and good sample size. Unstructured data covers the primary endpoint of the trial, which is overall response rate. A key learning is you need to choose a database that is fit-for-purpose with good quality.

H. Mark Lin, PhD
Senior Director, Global Evidence and Outcome Research in Oncology at Takeda

Interested in working with
Flatiron real-world data?

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