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Explore the latest insights, research, and stories from Flatiron.

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Point of Care
Real-World Evidence
Clinical Research
Flatiron Culture
Technology & Engineering

Point of Care

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Point of Care
Does EHR-embedded clinical decision support reduce care variation? Signs point to yes
Treatment decisions in oncology are highly complex due the enormous number of variables in each patient’s clinical and non-clinical circumstances and the rapid proliferation of available therapies for rare and common cancers.   In many cases, the sheer volume of data points to consider can be overwhelming to oncologists, especially general oncologists who care for patients with many different types of cancers on a regular basis. The challenge of trying to synthesize so much information can push ...
May 2023
Point of Care
How will AI impact the future of clinical decision support?
May 2023
Point of Care
CMS confirms Flatiron Assist™ clinical guidelines meet requirements of the Enhancing Oncology Model
April 2023
Point of Care
The Collective Responsibility for Driving Health Equity in Oncology
April 2023

Real-World Evidence

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Real-World Evidence
Unlocking the potential of real-world evidence: key learnings from ISPOR 2023
ISPOR 2023 yielded many key insights for our Real-World Evidence team to carry forward into their work to reimagine the infrastructure of cancer care. We’re sharing our top four below:  #1 Assessing fitness for purpose of real-world data for regulatory and health technology assessment (HTA) submissions necessitates quality framework consensus As the reliance on real-world data (RWD) continues to grow in regulatory and reimbursement decision-making, the need for a comprehensive, EHR-specific ...
May 2023
Real-World Evidence
The association between baseline hepatic or renal function and clinical outcomes for patients with NSCLC treated with a PD-1/PD-L1 blocking antibody using real-world and trials data
May 2023
Real-World Evidence
Clinico-Genomic Data is a Game Changer for Precision Oncology
March 2023
Real-World Evidence
Approach to machine learning for extraction of real-world data variables from electronic health records
March 2023

Clinical Research

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Clinical Research
[On Demand] Improving clinical research from within: bridging the gap between research and care
Within the vast industry of healthcare, it’s no surprise there are silos, namely the divide between traditional healthcare delivery and clinical research. However, the evolving landscape of modern technology enables and inspires new ways of working and collaborating in an effort to break down those same silos. It is possible to design studies better, identify and recruit trial-eligible patients, and improve data excellence enabled by data collection at the point of care – all the while reducing ...
March 2023
Clinical Research
Mechanisms for transferring structured and unstructured data from the EHR at the point of care into study EDC systems
March 2023
Clinical Research
Improving diversity in clinical trials by using real-world data to define eligibility criteria
February 2023
Clinical Research
The History of Flatiron Clinical Research
February 2023

Flatiron Culture

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Flatiron Culture
Evolving the Flatiron Brand
Flatiron today isn’t the same company as the one founded nearly eleven years ago. We’ve evolved. Over the course of the past decade plus, we’ve built upon the foundation of those early days and now have a legacy in technology and data science that’s propelling our forays into clinical research, clinical decision support, end-to-end evidence solutions, and global expansion.  These new endeavors mean that we’re even more poised to make accelerated progress toward our mission: improving and ...
March 2023
Flatiron Culture
Clinico-Genomic Data is a Game Changer for Precision Oncology
March 2023
Flatiron Culture
How Flatiron employee initiatives are helping the planet—and the bottom line
January 2023
Flatiron Culture
Why data and technology are essential to reimagining the infrastructure of cancer care
January 2023

Technology & Engineering

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Technology & Engineering
Clinico-Genomic Data is a Game Changer for Precision Oncology
Real-world clinico-genomic data has been recognized across healthcare as a catalyst to spur potentially life-changing advancements in cancer care. In 2016, Flatiron Health and Foundation Medicine (FMI) began collaborating on a powerful resource for precision oncology, called the Clinico-Genomic Database (CGDB) which combines patient level genomic data with clinical data, resulting in a more complete picture of patients living with cancer.  Let’s walk through how it works. The CGDB integrates ...
March 2023
Technology & Engineering
Why data and technology are essential to reimagining the infrastructure of cancer care
January 2023
Technology & Engineering
Achieving the impossible for rare populations: Leveraging technology to open opportunities for patients with hematologic malignancies
December 2022
Technology & Engineering
Scaling insights in cancer care with machine learning
December 2022