Protocol First joins Flatiron Health to advance clinical research. Read more
Clinical Research
Bridging the divide between clinical care and clinical research
For over 10 years, Flatiron has served as a leader in both EHR-technology and real-world evidence. Now, we’re transforming clinical research through technology that seamlessly integrates research into everyday clinical care.
Empowering and enabling smarter research
- Deep site integrations
Clinical trial technology deployed across a wide range of research sites: 75+ community clinics and 20+ Academic Medical Centers.
Scientific & thought leadershipClose thought partnership and support through in-house quantitative scientists, clinician investigators and regulatory experts.
Embedded research workflowsStrong expertise in integrating technology solutions seamlessly into sites’ clinical research workflows.
Data quality & expertiseHigh data quality standards as well as the ability to combine prospective and retrospective data in a centralized database.
Interoperable technologySoftware solutions built on FHIR standards to enable data sharing across the leading EHR and EDC systems.
EP 03 | Bridging the divide: Opportunities to integrate clinical research into everyday care
Case Study
Beat AML®
In 2016, the Leukemia and Lymphoma Society (LLS) established the Beat AML® trial with the aim of advancing the treatment paradigm for AML through collaboration across over 20+ sites, sponsors, and technology vendors.
In order to effectively run the coordination needed for this large master protocol, LLS sought a technology partner with capabilities to (1) enable remote access to source data, (2) facilitate data entry with EHR-to-EDC technology, and (3) provide an EDC system that can be seamlessly updated. LLS partnered with Flatiron (formerly Protocol First) to provide multiple eClinical solutions to meet the high demands and standards for Beat AML® with great success.
Read more about how innovative clinical trial technology helped enable the Beat AML® trial.
Study Results:
11 individual studies
60+ amendments
300,000+ pages of source uploaded
80% of monitoring time done remotely
12 sites using EHR-to-EDC technology
Source Upload, Clinical Pipe and P1 EDC
100+
clinical trials
50+
sponsors
20+
major Academic centers
Case Study
Prospective Clinico-Genomic Study
Flatiron Health, Foundation Medicine and Genentech partnered to develop a novel, low-interventional prospective study for patients living with advanced lung cancer 一 PCG. This study piloted the use of a technology-enabled prospective data collection platform and aimed to alleviate clinical trial operational challenges.
Read the full case study to learn more about Flatiron’s approach to Prospective Real-World Studies.
Study Results:
950 enrollments in 18 months
0 EDC fields needed; study data captured in the EHR
100% of surveyed sites said that they would run a similar study again
100% of participating sites liked answering queries directly in OncoTrials®
There’s a lot of human error components that can come with that when you’re moving a lot of data points, and you’re having to answer a lot of queries which also take time. For us, this is the first technology solution we’ve been presented with that really takes everything off the site.